Molecular Regulation of Heme Oxygenase-1 Expression by E2F Transcription Factor 2 in Lung Fibroblast Cells: Relevance to Idiopathic Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) is a fatal chronic lung disease. Heme oxygenase-1 (HMOX1/HO-1) is an enzyme that catalyzes the degradation of heme. The role of HO-1 in the pathogenesis of IPF has been studied; however, the molecular regulation of HO-1 and its role in IPF are still unclear. In th...

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Bibliographic Details

Published in:	Biomolecules
Main Authors:	Qinmao Ye, Sarah J. Taleb, Heather Wang, Narasimham L. Parinandi, Daniel J. Kass, Mauricio Rojas, Cankun Wang, Qin Ma, Jing Zhao, Yutong Zhao
Format:	Article
Language:	English
Published:	MDPI AG 2022-10-01
Subjects:	heme oxygenase-1/HO-1 gene suppression transcriptional factor E2F2 lung fibrosis
Online Access:	https://www.mdpi.com/2218-273X/12/10/1531