Centrosomal Protein 55 (CEP55) Drives Immune Exclusion and Resistance to Immune Checkpoint Inhibitors in Colorectal Cancer

Colorectal cancer (CRC) currently ranks as the third most common cancer in the United States, and its incidence is on the rise, especially among younger individuals. Despite the remarkable success of immune checkpoint inhibitors (ICIs) in various cancers, most CRC patients fail to respond due to int...

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Bibliographic Details

Published in:	Vaccines
Main Authors:	Dechen Wangmo, Travis J. Gates, Xianda Zhao, Ruping Sun, Subbaya Subramanian
Format:	Article
Language:	English
Published:	MDPI AG 2024-01-01
Subjects:	colorectal cancer CEP55 immune regulation T cells immune checkpoint inhibition
Online Access:	https://www.mdpi.com/2076-393X/12/1/63