The Synthesis and Biological Evaluation of Aloe-Emodin-Coumarin Hybrids as Potential Antitumor Agents

A series of novel aloe-emodin–coumarin hybrids were designed and synthesized. The antitumor activity of these derivatives was evaluated against five human tumor cell lines (A549, SGC-7901, HepG2, MCF-7 and HCT-8). Some of the synthesized compounds exhibited moderate to good activity against one or m...

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Bibliographic Details
Published in:Molecules
Main Authors: Hai Shang, Yue Hu, Jingrong Li, Lingyu Li, Yu Tian, Xiaoxue Li, Qi Wu, Zhongmei Zou
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Subjects:
Online Access:https://www.mdpi.com/1420-3049/27/19/6153