The male pachynema-specific protein MAPS drives phase separation in vitro and regulates sex body formation and chromatin behaviors in vivo

Summary: Dynamic chromosome remodeling and nuclear compartmentalization take place during mammalian meiotic prophase I. We report here that the crucial roles of male pachynema-specific protein (MAPS) in pachynema progression might be mediated by its liquid-liquid phase separation in vitro and in cel...

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Bibliographic Details

Published in:	Cell Reports
Main Authors:	Zexiong Lin, Dongliang Li, Jiahuan Zheng, Chencheng Yao, Dongteng Liu, Hao Zhang, Haiwei Feng, Chunxu Chen, Peng Li, Yuxiang Zhang, Binjie Jiang, Zhe Hu, Yu Zhao, Fu Shi, Dandan Cao, Kenny A. Rodriguez-Wallberg, Zheng Li, William S.B. Yeung, Louise T. Chow, Hengbin Wang, Kui Liu
Format:	Article
Language:	English
Published:	Elsevier 2024-01-01
Subjects:	CP: Molecular biology CP: Cell biology
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124723016625