APOE genotype and sex affect microglial interactions with plaques in Alzheimer’s disease mice

Abstract Microglia affect Alzheimer’s disease (AD) pathogenesis in opposing manners, by protecting against amyloid accumulation in early phases of the disease and promoting neuropathology in advanced stages. Recent research has identified specific microglial interactions with amyloid plaques that ex...

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書誌詳細

出版年:	Acta Neuropathologica Communications
主要な著者:	T. L. Stephen, M. Cacciottolo, D. Balu, T. E. Morgan, M. J. LaDu, C. E. Finch, C. J. Pike
フォーマット:	論文
言語:	英語
出版事項:	BMC 2019-05-01
主題:	Alzheimer’s disease Amyloid Apolipoprotein E Microglia Plaques Sex differences
オンライン･アクセス:	http://link.springer.com/article/10.1186/s40478-019-0729-z