Neurofilament light chain as a mediator between LRRK2 mutation and dementia in Parkinson’s disease

Abstract Elevated neurofilament light chain (NfL) levels have been associated with dementia in idiopathic Parkinson’s disease (iPD). To examine the baseline and longitudinal changes in NfL levels in GBA-PD, SNCA-PD, and LRRK2-PD and further investigate the association between these genetic mutations...

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Bibliographic Details

Published in:	npj Parkinson's Disease
Main Authors:	Dehao Yang, Haobo Xie, Sheng Wu, Chenxin Ying, Yiqun Chen, Yaoying Ge, Ruotong Yao, Kun Li, Zihan Jiang, Guangyong Chen
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-09-01
Online Access:	https://doi.org/10.1038/s41531-023-00572-3