Tunable cell differentiation via reprogrammed mating-type switching

Abstract This study introduces a synthetic biology approach that reprograms the yeast mating-type switching mechanism for tunable cell differentiation, facilitating synthetic microbial consortia formation and cooperativity. The underlying mechanism was engineered into a genetic logic gate capable of...

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Bibliographic Details

Published in:	Nature Communications
Main Authors:	Yu Chyuan Heng, Shohei Kitano, Adelia Vicanatalita Susanto, Jee Loon Foo, Matthew Wook Chang
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-09-01
Online Access:	https://doi.org/10.1038/s41467-024-52282-w