A multidisciplinary and structured approach for comprehensive evaluation of functional outcomes, adverse events, psychosocial outcomes and health-related quality of life after local therapy for bone sarcoma in children: protocol for a cross-sectional study

IntroductionBone sarcoma patients face intensive treatment, including life-changing local therapy, which impacts both short- and long-term functioning. Moreover, bone sarcoma survivors experience the highest burden of adverse events of all childhood cancer survivors. To address these issues, we set...

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Published in:	Frontiers in Pediatrics
Main Authors:	Leonie G. Tigelaar, Lianne M. Haveman, Willem P. Bekkering, Irene L. B. Oude Lansink, Christel D. Rohrich, Hinke Van der Hoek, Laura R. Beek, Jennifer Van Dijk, Marjolein E. M. Langemeijer, Relinde W. Slooff-Lentink, Alied M. Van der Aa-Van Delden, Heleen Maurice-Stam, Annemarie M. L. Peek, Helena J. H. Van der Pal, Maria M. W. Koopman, Leontien C. M. Kremer, Stijn J. Westerbos, Harm Van Tinteren, Jos A. M. Bramer, Michiel A. J. Van de Sande, Martha A. Grootenhuis, Hendrik W. B. Schreuder, Johannes H. M. Merks
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-04-01
Subjects:	adverse events bone sarcoma functional outcome orthopedic surgery pediatric oncology study protocol
Online Access:	https://www.frontiersin.org/articles/10.3389/fped.2025.1534153/full