The internal sequence of the peptide-substrate determines its N-terminus trimming by ERAP1.

<h4>Background</h4>Endoplasmic reticulum aminopeptidase 1 (ERAP1) trims N-terminally extended antigenic peptide precursors down to mature antigenic peptides for presentation by major histocompatibility complex (MHC) class I molecules. ERAP1 has unique properties for an aminopeptidase bei...

詳細記述

書誌詳細

出版年:	PLoS ONE
主要な著者:	Irini Evnouchidou, Frank Momburg, Athanasios Papakyriakou, Angeliki Chroni, Leondios Leondiadis, Shih-Chung Chang, Alfred L Goldberg, Efstratios Stratikos
フォーマット:	論文
言語:	英語
出版事項:	Public Library of Science (PLoS) 2008-01-01
オンライン･アクセス:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0003658&type=printable