Structure-Based High-Throughput Virtual Screening and Molecular Dynamics Simulation for the Discovery of Novel SARS-CoV-2 NSP3 Mac1 Domain Inhibitors

Since the emergence of SARS-CoV-2, many genetic variations within its genome have been identified, but only a few mutations have been found in nonstructural proteins (NSPs). Among this class of viral proteins, NSP3 is a multidomain protein with 16 different domains, and its largest domain is known a...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Viruses
المؤلفون الرئيسيون: Behnaz Yazdani, Hajar Sirous, Simone Brogi, Vincenzo Calderone
التنسيق: مقال
اللغة:الإنجليزية
منشور في: MDPI AG 2023-11-01
الموضوعات:
nonstructural proteins
NSP3
macrodomain
Mac1
ADRP
ADP ribose phosphatase
الوصول للمادة أونلاين:https://www.mdpi.com/1999-4915/15/12/2291

الانترنت

https://www.mdpi.com/1999-4915/15/12/2291

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