Pan-cancer tRNA-derived fragment CAT1 coordinates RBPMS to stabilize NOTCH2 mRNA to promote tumorigenesis

Summary: Transfer RNA-derived fragments (tRFs) are a class of small non-coding regulatory RNAs that are involved in the pathophysiology of many diseases. However, the role of tRFs in cancer progression remains largely elusive. Here, we demonstrate that a pan-cancer 3′-tRF, CAT1 (cancer associated tR...

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Bibliographic Details

Published in:	Cell Reports
Main Authors:	Mengqian Yu, Jiani Yi, Qiongzi Qiu, Dongxia Yao, Jia Li, Juze Yang, Chunyi Mi, Liyuan Zhou, Bingjian Lu, Weiguo Lu, Kejing Ying, Wantao Chen, Enguo Chen, Honghe Zhang, Zhimin Lu, Yan Lu, Pengyuan Liu
Format:	Article
Language:	English
Published:	Elsevier 2023-11-01
Subjects:	CP: Cancer CP: Molecular biology
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124723014201