SARS-CoV-2 neutralizing antibody specificities differ dramatically between recently infected infants and immune-imprinted individuals

ABSTRACT The immune response to viral infection is shaped by past exposures to related virus strains, a phenomenon known as imprinting. For severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), much of the population has been imprinted by a viral spike from an early strain, either through va...

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Bibliographic Details

Published in:	Journal of Virology
Main Authors:	Bernadeta Dadonaite, Allison R. Burrell, Jenni Logue, Helen Y. Chu, Daniel C. Payne, David B. Haslam, Mary A. Staat, Jesse D. Bloom
Format:	Article
Language:	English
Published:	American Society for Microbiology 2025-04-01
Subjects:	SARS-CoV-2 immunology virology evolution antibody repertoire antigenic variation
Online Access:	https://journals.asm.org/doi/10.1128/jvi.00109-25