Misfolding and aggregation in neurodegenerative diseases: protein quality control machinery as potential therapeutic clearance pathways

Abstract The primary challenge in today’s world of neuroscience is the search for new therapeutic possibilities for neurodegenerative disease. Central to these disorders lies among other factors, the aberrant folding, aggregation, and accumulation of proteins, resulting in the formation of toxic ent...

詳細記述

書誌詳細

出版年:	Cell Communication and Signaling
主要な著者:	Oliwia Koszła, Przemysław Sołek
フォーマット:	論文
言語:	英語
出版事項:	BMC 2024-08-01
主題:	α-synuclein β-amyloid Aggregates Chaperones Misfolded proteins Neurodegenerative disease
オンライン･アクセス:	https://doi.org/10.1186/s12964-024-01791-8