Identification of the Cysteine Protease Legumain as a Potential Chronic Hypoxia-Specific Multiple Myeloma Target Gene

Multiple myeloma (MM) is the second most common hematologic malignancy, which is characterized by clonal proliferation of neoplastic plasma cells in the bone marrow. This microenvironment is characterized by low oxygen levels (1–6% O<sub>2</sub>), known as hypoxia. For MM cells, hypoxia...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Cells
المؤلفون الرئيسيون: Ada-Sophia Clees, Verena Stolp, Björn Häupl, Dominik C. Fuhrmann, Frank Wempe, Marcel Seibert, Sarah Weber, Antje Banning, Ritva Tikkanen, Richard Williams, Bernhard Brüne, Hubert Serve, Frank Schnütgen, Ivana von Metzler, Nina Kurrle
التنسيق: مقال
اللغة:الإنجليزية
منشور في: MDPI AG 2022-01-01
الموضوعات:
multiple myeloma
chronic hypoxia
asparaginyl endopepdidase (AEP)
legumain
glycolysis
الوصول للمادة أونلاين:https://www.mdpi.com/2073-4409/11/2/292

الانترنت

https://www.mdpi.com/2073-4409/11/2/292

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