CD73 and PD-L1 dual blockade amplifies antitumor efficacy of SBRT in murine PDAC models

Background Stereotactic body radiotherapy (SBRT) induces immunogenic cell death, leading to subsequent antitumor immune response that is in part counterbalanced by activation of immune evasive processes, for example, upregulation of programmed cell death-ligand 1 (PD-L1) and adenosine generating enz...

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Bibliographic Details

Published in:	Journal for ImmunoTherapy of Cancer
Main Authors:	Jian Ye, Brian A Belt, David C Linehan, Tara G Vrooman, Carl J Johnston, Edith M Lord, Scott A Gerber, Nicholas W Gavras, David C Keeley, Angela L Hughson, Gary Hannon, Maggie L Lesch, Jim Eyles
Format:	Article
Language:	English
Published:	BMJ Publishing Group 2023-05-01
Online Access:	https://jitc.bmj.com/content/11/5/e006842.full