Regulation of the brain isoprenoids farnesyl- and geranylgeranylpyrophosphate is altered in male Alzheimer patients

Post-translational modification of small GTPases by farnesyl- (FPP) and geranylgeranylpyrophosphate (GGPP) has generated much attention due to their potential contribution to cancer, cardiovascular and neurodegenerative diseases. Prenylated proteins have been identified in numerous cell functions an...

詳細記述

書誌詳細

出版年:	Neurobiology of Disease
主要な著者:	Gunter P. Eckert, Gero P. Hooff, Dana M. Strandjord, Urule Igbavboa, Dietrich A. Volmer, Walter E. Müller, W. Gibson Wood
フォーマット:	論文
言語:	英語
出版事項:	Elsevier 2009-08-01
主題:	Alzheimer disease HMG-CoA reductase Isoprenoids Farnesylpyrophosphate Geranylgeranylpyrophosphate Prenylation
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S0969996109001028