Reactive Oxygen Species as Key Molecules in the Pathogenesis of Alcoholic Fatty Liver Disease and Nonalcoholic Fatty Liver Disease: Future Perspectives

Reactive oxygen species (ROS) are central to the progression of alcoholic fatty liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD). In ALD, ROS arise from alcohol metabolism (CYP2E1 and ADH/ALDH2), causing oxidative damage and fibrosis. In NAFLD, mitochondrial dysfunction, ER stress, a...

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Bibliographic Details

Published in:	Current Issues in Molecular Biology
Main Authors:	Zhiqing Zhang, Hong Yang, Fei Han, Peng Guo
Format:	Article
Language:	English
Published:	MDPI AG 2025-06-01
Subjects:	reactive oxygen species alcoholic fatty liver disease nonalcoholic fatty liver disease
Online Access:	https://www.mdpi.com/1467-3045/47/6/464