Incorporating physics to overcome data scarcity in predictive modeling of protein function: A case study of BK channels.

Machine learning has played transformative roles in numerous chemical and biophysical problems such as protein folding where large amount of data exists. Nonetheless, many important problems remain challenging for data-driven machine learning approaches due to the limitation of data scarcity. One ap...

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Bibliographic Details
Published in:PLoS Computational Biology
Main Authors: Erik Nordquist, Guohui Zhang, Shrishti Barethiya, Nathan Ji, Kelli M White, Lu Han, Zhiguang Jia, Jingyi Shi, Jianmin Cui, Jianhan Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-09-01
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1011460&type=printable