Amentoflavone attenuates abdominal aortic aneurysm progression by suppressing vascular smooth muscle cell phenotypic switching via targeting NF-κB-MMP2/9 axis

Abstract Objective To investigate the role and mechanism of amentoflavone (AMF) in abdominal aortic aneurysm (AAA) pathogenesis, providing novel therapeutic candidates and theoretical foundations. Methods ①Animal studies: AAA models were induced by angiotensin Ⅱ (Ang Ⅱ) in 6 to 8-week-old mal...

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發表在:	陆军军医大学学报
Main Authors:	LIN Xin, YU Junyi
格式:	Article
語言:	中文
出版:	Editorial Office of Journal of Army Medical University 2026-05-01
主題:	abdominal aortic aneurysm vascular smooth muscle cells amentoflavone matrix metalloproteinase nf-κb signaling
在線閱讀:	https://aammt.tmmu.edu.cn/thesisDetails#10.16016/j.2097-0927.202604083&lang=en