CDK4/6 inhibitors display a class effect in inducing differentiation of neuroblastoma cells [version 2; peer review: 1 approved, 2 approved with reservations]

Background Neuroblastoma is the most common extracranial solid tumour in infants and children, accounting for approximately 15% of paediatric cancer mortality. These tumours are unique in that a subset, namely stage MS, frequently undergo spontaneous regression or differentiation. Differentiation th...

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Bibliographic Details

Published in:	Wellcome Open Research
Main Authors:	Anna Philpott, Fiona M. Y. Abou Grealy, Kirsty M. Ferguson
Format:	Article
Language:	English
Published:	Wellcome 2025-09-01
Subjects:	neuroblastoma CDK4/6 retinoic acid differentiation palbociclib abemaciclib eng
Online Access:	https://wellcomeopenresearch.org/articles/9-667/v2