Modulation of Anxiety-Like Behavior in Sildenafil Citrate-Treated Mice Placed in an Elevated Plus-Maze

Introduction: Sildenafil, a phosphodiesterase-5 (PDE5) inhibitor, may have various effects on the central nervous system via the nitric oxide (NO)-cyclic guanosine monophosphate (cGMP) pathway. Preclinical studies have shown the controversial effect of sildenafil on anxiety-like behavior in animals....

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Bibliographic Details

Published in:	Basic and Clinical Neuroscience
Main Authors:	Siamak Shahidi, Nasrin Hashemi-Firouzi, Minoo Mahmoodi
Format:	Article
Language:	English
Published:	Iran University of Medical Sciences 2011-08-01
Subjects:	Anxiety Sildenafil Acute Elevated Plus-Maze Mice.
Online Access:	http://bcn.iums.ac.ir/browse.php?a_code=A-10-1-76&slc_lang=en&sid=1