Effect of the renin-angiotensin system on the exacerbation of adrenal glucocorticoid steroidogenesis in diabetic mice: Role of angiotensin-II type 2 receptor

Prior investigation shows an increase in the activity of both hypothalamus-pituitary-adrenal (HPA) axis and the renin-angiotensin system (RAS) in diabetic patients. Moreover, activation of angiotensin-II type 1 receptor (AT1) has been associated with adrenal steroidogenesis. This study investigates...

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Bibliographic Details

Published in:	Frontiers in Endocrinology
Main Authors:	Amanda da Silva Chaves, Nathalia Santos Magalhães, Daniella Bianchi Reis Insuela, Patrícia Machado Rodrigues E. Silva, Marco Aurélio Martins, Vinicius Frias Carvalho
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-11-01
Subjects:	angiotensin II receptors diabetes glucocorticoids renin-angiotensin system steroidogenesis
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2022.1040040/full