Stability Assessment of Four Chimeric Proteins for Human Chagas Disease Immunodiagnosis

The performance of an immunoassay relies on antigen-antibody interaction; hence, antigen chemical stability and structural integrity are paramount for an efficient assay. We conducted a functional, thermostability and long-term stability analysis of different chimeric antigens (IBMP), in order to as...

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Bibliographic Details
Published in:Biosensors
Main Authors: Paola Alejandra Fiorani Celedon, Leonardo Maia Leony, Ueriton Dias Oliveira, Natália Erdens Maron Freitas, Ângelo Antônio Oliveira Silva, Ramona Tavares Daltro, Emily Ferreira Santos, Marco Aurélio Krieger, Nilson Ivo Tonin Zanchin, Fred Luciano Neves Santos
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Subjects:
Chagas disease
immunoassays
chimeric proteins
stability
Online Access:https://www.mdpi.com/2079-6374/11/8/289

Internet

https://www.mdpi.com/2079-6374/11/8/289

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