Shedding light on DNA methylation and its clinical implications: the impact of long-read-based nanopore technology

Abstract DNA methylation is an essential epigenetic mechanism for regulation of gene expression, through which many physiological (X-chromosome inactivation, genetic imprinting, chromatin structure and miRNA regulation, genome defense, silencing of transposable elements) and pathological processes (...

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Bibliographic Details

Published in:	Epigenetics & Chromatin
Main Authors:	Alexandra Chera, Mircea Stancu-Cretu, Nicolae Radu Zabet, Octavian Bucur
Format:	Article
Language:	English
Published:	BMC 2024-12-01
Subjects:	Nanopore sequencing Long-read sequencing DNA methylation Epigenomics Methylome
Online Access:	https://doi.org/10.1186/s13072-024-00558-2