Potential effect of FLASH radiotherapy on testicular damage: a review of current evidence

Radiotherapy is a major source of ionizing radiation that adversely affects the male reproductive system. FLASH radiotherapy (FLASH-RT), a novel technique delivering ultra-high dose rate (UHDR) radiation, has shown promise in reducing normal tissue damage while maintaining antitumor efficacy—a pheno...

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Bibliographic Details

Published in:	Frontiers in Oncology
Main Authors:	Xiaoyu Zhi, Lehui Du, YaNan Han, Weiwei Li, Pei Zhang, Xingdong Guo, Yuan Wang, Na Ma, Xiao Lei, Baolin Qu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-09-01
Subjects:	FLASH irradiation ultra-high dose rate radiation damage testicular tissue reproductive cells
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2025.1618270/full