AP2X-1 is a negative regulator of Toxoplasma gondii sexual commitment

ABSTRACT Toxoplasma gondii is a widespread protozoan with a complex life cycle, characterized by transitions between various hosts and developmental stages, each tailored to a specific niche within its host. However, the regulatory mechanisms governing these life cycle transitions are not well under...

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Bibliographic Details

Published in:	mBio
Main Authors:	Li-Xiu Sun, Meng Wang, Tian-Yu Zhang, Hany M. Elsheikha, Zhi-Wei Zhang, Xiao-Nan Zheng, Bao-Quan Fu, Xing-Quan Zhu, Guo-Hua Liu, Jin-Lei Wang
Format:	Article
Language:	English
Published:	American Society for Microbiology 2025-09-01
Subjects:	Toxoplasma gondii AP2X-1 HDAC3/MORC complex gene expression sexual development transcription
Online Access:	https://journals.asm.org/doi/10.1128/mbio.00052-25