Knock-Out of Retrovirus Receptor Gene <i>Tva</i> in the Chicken Confers Resistance to Avian Leukosis Virus Subgroups A and K and Affects Cobalamin (Vitamin B₁₂)-Dependent Level of Methylmalonic Acid

The chicken Tva cell surface protein, a member of the low-density lipoprotein receptor family, has been identified as an entry receptor for avian leukosis virus of classic subgroup A and newly emerging subgroup K. Because both viruses represent an important concern for the poultry industry, we intro...

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Bibliographic Details

Published in:	Viruses
Main Authors:	Anna Koslová, Pavel Trefil, Jitka Mucksová, Veronika Krchlíková, Jiří Plachý, Jakub Krijt, Markéta Reinišová, Dana Kučerová, Josef Geryk, Jiří Kalina, Filip Šenigl, Daniel Elleder, Viktor Kožich, Jiří Hejnar
Format:	Article
Language:	English
Published:	MDPI AG 2021-12-01
Subjects:	avian leukosis virus subgroups A/K <i>tva</i> gene editing in chicken vitamin B<sub>12</sub>/cobalamin
Online Access:	https://www.mdpi.com/1999-4915/13/12/2504