Large-scale serum protein biomarkers discovery associated with function and clinical milestones in Duchenne muscular dystrophy

Abstract Duchenne muscular dystrophy (DMD) is characterized by progressive muscle wasting and weakness. Serum proteins may offer insight into disease processes and clinical decline. This observational study uses the 7 K SomaScan® assay to discover serum proteins associated with muscle function and d...

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Bibliographic Details
Published in:Nature Communications
Main Authors: N. A. Ikelaar, A. M. Barnard, S.W.M. Eng, Shahrzad Hosseini Vajargah, K.C.H. Ha, H. E. Kan, K. Vandenborne, E. H. Niks, G. A. Walter, P. Spitali
Format: Article
Language:English
Published: Nature Portfolio 2025-10-01
Online Access:https://doi.org/10.1038/s41467-025-64146-y