Effects of mesenchymal stromal cells and human recombinant Nerve Growth Factor delivered by bioengineered human corneal lenticule on an innovative model of diabetic retinopathy

IntroductionDiabetic retinopathy (DR) is a microvascular complication of diabetes in which neurodegeneration has been recently identified as a driving force. In the last years, mesenchymal stromal cells (MSCs) and neurotrophins like Nerve Growth Factor (NGF), have garnered significant attention as i...

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Published in:	Frontiers in Endocrinology
Main Authors:	Letizia Pelusi, Jose Hurst, Nicola Detta, Caterina Pipino, Alessia Lamolinara, Gemma Conte, Rodolfo Mastropasqua, Marcello Allegretti, Nadia Di Pietrantonio, Tiziana Romeo, Mona El Zarif, Mario Nubile, Laura Guerricchio, Sveva Bollini, Assunta Pandolfi, Sven Schnichels, Domitilla Mandatori
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-10-01
Subjects:	diabetic retinopathy mesenchymal stromal cells rhNGF corneal lenticule ocular delivery
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2024.1462043/full