IFNγ-Treated Macrophages Induce EMT through the WNT Pathway: Relevance in Crohn’s Disease

Background: Fibrosis is a common complication of Crohn’s disease (CD) in which macrophages play a central role. Epithelial-mesenchymal transition (EMT) and the WNT pathway have been associated with fibrosis. We aim to analyse the relevance of the tissue microenvironment in macrophage phenotype and t...

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Bibliographic Details

Published in:	Biomedicines
Main Authors:	Dulce C. Macias-Ceja, Sandra Coll, Cristina Bauset, Marta Seco-Cervera, Laura Gisbert-Ferrándiz, Francisco Navarro, Jesus Cosin-Roger, Sara Calatayud, María D. Barrachina, Dolores Ortiz-Masia
Format:	Article
Language:	English
Published:	MDPI AG 2022-05-01
Subjects:	Crohn disease IFNγ Epithelial Mesenchymal Transition (EMT) macrophages fibrosis
Online Access:	https://www.mdpi.com/2227-9059/10/5/1093