Toll-like receptors in systemic lupus erythematosus: potential for personalized treatment

Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by the loss of tolerance to self-nuclear antigens. The symptoms of SLE, progression of pathology and the array of auto-antibodies present in the serum differ significantly from patient to patient, which calls for a pers...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Teja eCelhar, Anna-Marie eFairhurst
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2014-12-01
Subjects:	pharmacogenomics TLR7 TLR9 systemic lupus erythematosus Type I Interferons
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00265/full