Feasibility of azacitidine added to standard chemotherapy in older patients with acute myeloid leukemia--a randomised SAL pilot study.

Older patients with acute myeloid leukemia (AML) experience short survival despite intensive chemotherapy. Azacitidine has promising activity in patients with low proliferating AML. The aim of this dose-finding part of this trial was to evaluate feasibility and safety of azacitidine combined with a...

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Bibliographic Details
Published in:PLoS ONE
Main Authors: Utz Krug, Anja Koschmieder, Daniela Schwammbach, Joachim Gerss, Nicola Tidow, Björn Steffen, Gesine Bug, Christian H Brandts, Markus Schaich, Christoph Röllig, Christian Thiede, Richard Noppeney, Matthias Stelljes, Thomas Büchner, Steffen Koschmieder, Ulrich Dührsen, Hubert Serve, Gerhard Ehninger, Wolfgang E Berdel, Carsten Müller-Tidow
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Online Access:http://europepmc.org/articles/PMC3534078?pdf=render