IgG and IgM cooperate in coating of intestinal bacteria in IgA deficiency

Abstract Immunoglobulin A (IgA) is acknowledged to play a role in the defence of the mucosal barrier by coating microorganisms. Surprisingly, IgA-deficient humans exhibit few infection-related complications, raising the question if the more specific IgG may help IgM in compensating for the lack of I...

Full description

Bibliographic Details
Published in:Nature Communications
Main Authors: Carsten Eriksen, Janne Marie Moll, Pernille Neve Myers, Ana Rosa Almeida Pinto, Niels Banhos Danneskiold-Samsøe, Rasmus Ibsen Dehli, Lisbeth Buus Rosholm, Marlene Danner Dalgaard, John Penders, Daisy MAE Jonkers, Qiang Pan-Hammarström, Lennart Hammarström, Karsten Kristiansen, Susanne Brix
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Online Access:https://doi.org/10.1038/s41467-023-44007-2