Exhausting circ_0136474 and Restoring miR-766-3p Attenuate Chondrocyte Oxidative Injury in IL-1β-Induced Osteoarthritis Progression Through Regulating DNMT3A

Circular RNA circ_0136474 is a new contributor of human osteoarthritis (OA) by suppressing chondrocyte proliferation. However, its role and mechanism in OA chondrocyte injury remain ill defined. Herein, we performed real-time quantitative PCR to detect RNA expression of circ_0136474, microRNA (miR)-...

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Bibliographic Details

Published in:	Frontiers in Genetics
Main Authors:	Haiquan Zhu, Shaobo Zhu, Xiuchao Shang, Xiangsheng Meng, Sheng Jing, Li Yu, Yu Deng
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-05-01
Subjects:	circ_0136474 miR-766-3p DNMT3A chondrocytes osteoarthritis
Online Access:	https://www.frontiersin.org/articles/10.3389/fgene.2021.648709/full