In Vitro Mineralisation of Tissue-Engineered Cartilage Reduces Endothelial Cell Migration, Proliferation and Tube Formation

Tissue engineering bone via endochondral ossification requires the generation of a cartilage template which undergoes vascularisation and remodelling. While this is a promising route for bone repair, achieving effective cartilage vascularisation remains a challenge. Here, we investigated how mineral...

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Bibliographic Details

Published in:	Cells
Main Authors:	Encheng Ji, Lieke Leijsten, Janneke Witte-Bouma, Adelin Rouchon, Nunzia Di Maggio, Andrea Banfi, Gerjo J. V. M. van Osch, Eric Farrell, Andrea Lolli
Format:	Article
Language:	English
Published:	MDPI AG 2023-04-01
Subjects:	bone tissue engineering endochondral ossification angiogenesis mineralisation mesenchymal stromal cells
Online Access:	https://www.mdpi.com/2073-4409/12/8/1202