Brain Noradrenergic Innervation Supports the Development of Parkinson’s Tremor: A Study in a Reserpinized Rat Model

The pathophysiology of tremor in Parkinson’s disease (PD) is evolving towards a complex alteration to monoaminergic innervation, and increasing evidence suggests a key role of the locus coeruleus noradrenergic system (LC-NA). However, the difficulties in imaging LC-NA in patients challenge its direc...

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Bibliographic Details
Published in:Cells
Main Authors: Nicoló Gabriele Pozzi, Francesco Bolzoni, Gabriele Eliseo Mario Biella, Gianni Pezzoli, Chi Wang Ip, Jens Volkmann, Paolo Cavallari, Esther Asan, Ioannis Ugo Isaias
Format: Article
Language:English
Published: MDPI AG 2023-10-01
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Online Access:https://www.mdpi.com/2073-4409/12/21/2529