Human umbilical cord mesenchymal stem cell derived exosomes (HUCMSC-exos) recovery soluble fms-like tyrosine kinase-1 (sFlt-1)-induced endothelial dysfunction in preeclampsia

Abstract Background Preeclampsia is a unique multisystem disorder that affects 5–8% of pregnancies. A high level of soluble fms-like tyrosine kinase-1 (sFlt-1) is a hallmark of preeclampsia that causes endothelial dysfunction. Exosomes derived from mesenchymal stem cells (MSCs) have been indicated t...

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Bibliographic Details

Published in:	European Journal of Medical Research
Main Authors:	Xinwen Chang, Qizhi He, Mengtian Wei, Linyan Jia, Yingying Wei, Yiding Bian, Tao Duan, Kai Wang
Format:	Article
Language:	English
Published:	BMC 2023-08-01
Subjects:	Preeclampsia Mesenchymal stem cell Exosomes Angiogenesis Soluble fms-like tyrosine kinase-1/sFlt-1
Online Access:	https://doi.org/10.1186/s40001-023-01182-8