Achyranthes bidentata polysaccharides attenuate hypoxic renal injury by reducing neutrophil extracellular traps and suppressing the NLRP3/ASC/caspase-1 pathway: a preliminary study

AimThe aim of this study was to investigate whether Achyranthes bidentata polysaccharides (ABPSs) alleviate hypoxic renal injury (HRI) and the possible mechanism.MethodsThe HRI rat model was established using a hypobaric hypoxia chamber. Rats were divided into a control group, a hypoxia group, low-d...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Kai Li, JingWei Fang, GuangMin Xie, FangNing Wei, JunYing Lv
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-10-01
Subjects:	Achyranthes bidentata polysaccharides neutrophil extracellular traps oxidative stress hypoxic renal injury acute kidney injury
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1606851/full