The PB2 Polymerase Host Adaptation Substitutions Prime Avian Indonesia Sub Clade 2.1 H5N1 Viruses for Infecting Humans

Significantly higher numbers of human infections with H5N1 virus have occurred in Indonesia and Egypt, compared with other affected areas, and it is speculated that there are specific viral factors for human infection with avian H5N1 viruses in these locations. We previously showed PB2-K526R is pres...

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Bibliographic Details

Published in:	Viruses
Main Authors:	Pui Wang, Wenjun Song, Bobo Wing-Yee Mok, Min Zheng, Siu-Ying Lau, Siwen Liu, Pin Chen, Xiaofeng Huang, Honglian Liu, Conor J. Cremin, Honglin Chen
Format:	Article
Language:	English
Published:	MDPI AG 2019-03-01
Subjects:	Influenza virus H5N1 PB2 host adaptation RNP cross species transmission
Online Access:	https://www.mdpi.com/1999-4915/11/3/292