In vivo transcriptomic profiling using cell encapsulation identifies effector pathways of systemic aging

Sustained exposure to a young systemic environment rejuvenates aged organisms and promotes cellular function. However, due to the intrinsic complexity of tissues it remains challenging to pinpoint niche-independent effects of circulating factors on specific cell populations. Here, we describe a meth...

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Bibliographic Details

Published in:	eLife
Main Authors:	Omid Mashinchian, Xiaotong Hong, Joris Michaud, Eugenia Migliavacca, Gregory Lefebvre, Christophe Boss, Filippo De Franceschi, Emmeran Le Moal, Jasmin Collerette-Tremblay, Joan Isern, Sylviane Metairon, Frederic Raymond, Patrick Descombes, Nicolas Bouche, Pura Muñoz-Cánoves, Jerome N Feige, C Florian Bentzinger
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2022-03-01
Subjects:	aging cell encapsulation transcriptomics myogenic progenitors MuSCs satellite cells
Online Access:	https://elifesciences.org/articles/57393