Cetuximab and anemia prevention in head and neck cancer patients undergoing radiotherapy

Abstract Background Epidermal growth factor receptor (EGFR) activation is associated with increased production of interleukin 6 (IL6), which is intensified by radiotherapy (RT) induced inflammatory response. Elevated IL6 levels intensifies RT-induced anemia by upregulating hepcidin causing functiona...

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Bibliographic Details

Published in:	BMC Cancer
Main Authors:	Lucas Maahs, Ahmed I. Ghanem, Radhika Gutta, Amy Tang, Swarn Arya, Zaid Al Saheli, Haythem Ali, Steven Chang, Samantha Tam, Vivian Wu, Farzan Siddiqui, Jawad Sheqwara
Format:	Article
Language:	English
Published:	BMC 2022-06-01
Subjects:	Head and neck cancer Squamous cell carcinoma Concomitant cetuximab Radiation therapy Radiotherapy induced anemia Anemia
Online Access:	https://doi.org/10.1186/s12885-022-09708-9