Current status and future directions of high-throughput ADME screening in drug discovery

During the last decade high-throughput in vitro absorption, distribution, metabolism and excretion (HT-ADME) screening has become an essential part of any drug discovery effort of synthetic molecules. The conduct of HT-ADME screening has been “industrialized” due to the extensive development of soft...

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Bibliographic Details

Published in:	Journal of Pharmaceutical Analysis
Main Author:	Wilson Z. Shou
Format:	Article
Language:	English
Published:	Elsevier 2020-06-01
Subjects:	In vitro HT-ADME Automation Bioanalysis Mass spectrometry Acoustic ejection mass spectrometry
Online Access:	http://www.sciencedirect.com/science/article/pii/S2095177920302562