ASSOCIATION OF POLYMORPHISM IN PCSK9 GENE WITH LIPID PR OFILE IN RUSSIAN POPULATION

Background and aims: mutations in LDLR, APOB, PCSK9 genes determine the development of autosomal dominant forms of familial hypercholesterolemia. The PCSK9 gene encodes an enzyme involved in the metabolism of low density lipoprotein (LDL) by post-transcriptional regulation of the LDL receptors. Purp...

Full description

Bibliographic Details

Published in:	Атеросклероз
Main Authors:	K. S. Astrakova, E. V. Shakhtshneider, D. E. Ivanoshchuk, P. S. Orlov, Yu. I. Ragino, M. I. Voevoda
Format:	Article
Language:	Russian
Published:	Siberian Branch of Russian Academy of Sciences, Research Institute of Internal and Preventive Medicine, branch of the Institute of Cytology and Genetics 2016-06-01
Subjects:	familial hypercholesterolemia proprotein convertase subtilisin/kexin 9 gene population
Online Access:	https://ateroskleroz.elpub.ru/jour/article/view/13/13