Antibacterial Profile of a Microbicidal Agent Targeting Tyrosine Phosphatases and Redox Thiols, Novel Drug Targets

The activity profile of a protein tyrosine phosphatase (PTP) inhibitor and redox thiol oxidant, nitropropenyl benzodioxole (NPBD), was investigated across a broad range of bacterial species. In vitro assays assessed inhibitory and lethal activity patterns, the induction of drug variants on long term...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Antibiotics
المؤلفون الرئيسيون: Kylie White, Gina Nicoletti, Hugh Cornell
التنسيق: مقال
اللغة:الإنجليزية
منشور في: MDPI AG 2021-10-01
الموضوعات:
antimicrobial
nitropropenyl benzodioxole
nitroalkenyl benzenes
tyrosine signaling
protein tyrosine phosphatase inhibitor
thiol oxidant
الوصول للمادة أونلاين:https://www.mdpi.com/2079-6382/10/11/1310

الانترنت

https://www.mdpi.com/2079-6382/10/11/1310

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