RNA Binding Suppresses Tsg101 Recognition of Ub-Modified Gag and Facilitates Recruitment to the Plasma Membrane

The ESCRT-I factor Tsg101 is essential for sorting endocytic cargo and is exploited by viral pathogens to facilitate egress from cells. Both the nucleocapsid (NC) domain and p6 domain in HIV-1 Gag contribute to recruitment of the protein. However, the role of NC is unclear when the P(S/T)AP motif in...

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發表在:	Viruses
Main Authors:	Susan M. Watanabe, Madeleine Strickland, Nico Tjandra, Carol A. Carter
格式:	Article
語言:	英语
出版:	MDPI AG 2020-04-01
主題:	HIV Gag Tsg101 ESCRT ubiquitin RNA
在線閱讀:	https://www.mdpi.com/1999-4915/12/4/447