Does HLA explain the high incidence of childhood-onset type 1 diabetes in the Canary Islands? The role of Asp57 DQB1 molecules

Abstract The Canary Islands inhabitants, a recently admixed population with significant North African genetic influence, has the highest incidence of childhood-onset type 1 diabetes (T1D) in Spain and one of the highest in Europe. HLA accounts for half of the genetic risk of T1D. Aims To characteriz...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:BMC Pediatrics
المؤلفون الرئيسيون: Yeray Nóvoa-Medina, Itahisa Marcelino-Rodriguez, Nicolás M. Suárez, Marta Barreiro-Bautista, Eva Rivas-García, Santiago Sánchez-Alonso, Gema González-Martínez, Sofía Quinteiro-González, Ángela Domínguez, María Cabrera, Sara López, Svetlana Pavlovic, Carlos Flores, Gran Canarian Diabetes and Obesity Research Group, Ana M. Wägner
التنسيق: مقال
اللغة:الإنجليزية
منشور في: BMC 2024-09-01
الموضوعات:
Genetics
HLA
Pediatrics
Type 1 diabetes
الوصول للمادة أونلاين:https://doi.org/10.1186/s12887-024-04983-w

الانترنت

https://doi.org/10.1186/s12887-024-04983-w

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