An Optimal Ubiquitin-Proteasome Pathway in the Nervous System: The Role of Deubiquitinating Enzymes

The Ubiquitin-Proteasome Pathway (UPP), which is critical for normal function in the nervous system and is implicated in various neurological diseases, requires the small modifier protein ubiquitin to accomplish its duty of selectively degrading short-lived, abnormal or misfolded proteins. Over the...

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書誌詳細

出版年:	Frontiers in Molecular Neuroscience
主要な著者:	Gorica eRistic, Wei-Ling eTsou, Sokol V Todi
フォーマット:	論文
言語:	英語
出版事項:	Frontiers Media S.A. 2014-08-01
主題:	Brain Neuron glia neurodegeneration synapse polyglutamine
オンライン･アクセス:	http://journal.frontiersin.org/Journal/10.3389/fnmol.2014.00072/full