Hyperpolarized 13C pyruvate magnetic resonance spectroscopy for in vivo metabolic phenotyping of rat HCC

Abstract The in vivo assessment of tissue metabolism represents a novel strategy for the evaluation of oncologic disease. Hepatocellular carcinoma (HCC) is a high-prevalence, high-mortality tumor entity often discovered at a late stage. Recent evidence indicates that survival differences depend on m...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Elisabeth Bliemsrieder, Georgios Kaissis, Martin Grashei, Geoffrey Topping, Jennifer Altomonte, Christian Hundshammer, Fabian Lohöfer, Irina Heid, Dominik Keim, Selamawit Gebrekidan, Marija Trajkovic-Arsic, Aline Winkelkotte, Katja Steiger, Roman Nawroth, Jens Siveke, Markus Schwaiger, Marcus Makowski, Franz Schilling, Rickmer Braren
Format:	Article
Language:	English
Published:	Nature Portfolio 2021-01-01
Online Access:	https://doi.org/10.1038/s41598-020-80952-4