In vitro differentiation of common lymphoid progenitor cells into B cell using stromal cell free culture system

Abstract The OP9 culture system is an important in vitro model for B cell development. However, the complex nature of operations and the intrinsic variability of stromal cell functionality, which can be influenced by factors such as radiation exposure or contamination, pose considerable challenges t...

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書目詳細資料
發表在:BMC Immunology
Main Authors: Pan Yang, Xiaoling Chen, Hao Wen, Meiling Yu, Haili Yu, Li Wang, Liang Gong, Lintao Zhao
格式: Article
語言:英语
出版: BMC 2025-03-01
主題:
在線閱讀:https://doi.org/10.1186/s12865-025-00694-8