Tumor regression and immunity in combination therapy with anti-CEA chimeric antigen receptor T cells and anti-CEA-IL2 immunocytokine

Targeted immunotherapy of solid cancers with chimeric antigen receptor (CAR) T cells and immunocytokines are attractive options in that they both rely on the specificity of tumor-targeted antibodies. Since carcinoembryonic antigen (CEA) expression in both colon and breast cancers is correlated with...

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Bibliographic Details

Published in:	OncoImmunology
Main Authors:	Seung E. Cha, Maciej Kujawski, Paul J. Yazaki, Christine Brown, John E. Shively
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2021-01-01
Subjects:	carcinoembryonic antigen (cea) chimeric antigen receptor t cells (car t) immunocytokine lymphodepletion cea transgenic mice tumor immunity
Online Access:	http://dx.doi.org/10.1080/2162402X.2021.1899469